29444-03-9
Chemical Structure
Jatrophone
- CAS No.: 29444-03-9
- Formula:C20H24O3
- Molecular Weight:312.40
IUPAC Name: (2R,3aR,9Z,12Z)-2,5,8,8,12-pentamethyl-2,3,7,8-tetrahydro-3a,6-epoxycyclopenta[12]annulene-4,11-dione
InChIKey: MJNNONLDVCCGCA-NNFBGVLYSA-N
SMILES: O=C1[C@]2(O3)C(/C=C(C(/C=C\C(C)(C)CC3=C1C)=O)/C)=C[C@H](C)C2
Biological Activity: Jatrophone is a diterpenoid with anticancer activity isolated from Jatropha isabelli. Jatrophone interferes with the Wnt/β-catenin pathway to inhibit the proliferation and epithelial-mesenchymal transition (EMT) of triple-negative breast cancer cells.
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Jatrophone | Jatrophone is a diterpenoid with anticancer activity isolated from Jatropha isabelli. Jatrophone interferes with the Wnt/β-catenin pathway to inhibit the proliferation and epithelial-mesenchymal transition (EMT) of triple-negative breast cancer cells. | |||||||||||||||||||||
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Keywords