3052114-77-6
3052114-77-6
Chemical Structure
PROTAC PD-L1 degrader-1
- CAS No.: 3052114-77-6
- Formula:C45H55N5O7
- Molecular Weight:777.95
InChIKey: TVCUEWZCGMZLHG-UHFFFAOYSA-N
SMILES: O=C(NCCNCC1=CC=C(OCC2=C(C)C(C3=CC=CC=C3)=CC=C2)N=C1OC)CCCCCCCCNC(COC4=CC=C(C(CC5)C(NC5=O)=O)C=C4)=O
Biological Activity:
PROTAC PD-L1 degrader-1 is a CRBN-based PD-L1-PROTAC degrader with a notable PD-L1 protein degradation capability. PROTAC PD-L1 degrader-1 shows potent PD-L1 degradation in 4T1 cells with a DC50 of 0.609 μM. PROTAC PD-L1 degrader-1 can be used for the study of breast cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PROTAC PD-L1 degrader-1 | 99.79% | PROTAC PD-L1 degrader-1 is a CRBN-based PD-L1-PROTAC degrader with a notable PD-L1 protein degradation capability. PROTAC PD-L1 degrader-1 shows potent PD-L1 degradation in 4T1 cells with a DC50 of 0.609 μM. PROTAC PD-L1 degrader-1 can be used for the study of breast cancer. |
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References
Keywords
