446020-51-5
446020-51-5
Chemical Structure
SB-656104
- CAS No.: 446020-51-5
- Formula:C25H30ClN3O3S
- Molecular Weight:488.04
IUPAC Name: (R)-6-((2-(2-(4-(4-chlorophenoxy)piperidin-1-yl)ethyl)pyrrolidin-1-yl)sulfonyl)-1H-indole
InChIKey: QEGMGDYIJDZJCI-OAQYLSRUSA-N
SMILES: O=S(N1[C@H](CCC1)CCN2CCC(CC2)OC3=CC=C(C=C3)Cl)(C4=CC=C(C=CN5)C5=C4)=O
Biological Activity: SB-656104 is a potent antagonist of 5-HT7 receptor, with the pKi of 8.70, blocking 5-carboxamidotryptamine (5-CT) stimulated adenylyl cyclase activity[1].
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SB-656104 | SB-656104 is a potent antagonist of 5-HT7 receptor, with the pKi of 8.70, blocking 5-carboxamidotryptamine (5-CT) stimulated adenylyl cyclase activity. | |||||||||||||||||||||
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References
Keywords
