51053-39-5
Chemical Structure
Deoxaphomin
- CAS No.: 51053-39-5
- Formula:C29H37NO4
- Molecular Weight:463.61
InChIKey: GPCJCBIEJCXNKC-TYHYBEHESA-N
SMILES: O=C1[C@]23[C@]([C@@H](C([C@H]([C@]2([H])/C=C/C[C@@H](CCC[C@H](/C=C/C3=O)O)C)O)=C)C)([H])[C@@H](N1)CC4=CC=CC=C4
Biological Activity: Deoxaphomin is a cytochalasin. Deoxaphomin inhibits Actin filament elongation and reduces the viscosity of polymerized actin filaments. Deoxaphomin induces rounding of fibroblasts, contraction of actin cables, formation of actin-containing hairy structures, and formation of actin-containing cytoplasmic rodlets in fibroblasts. Deoxaphomin inhibits membrane ruffling in fibroblasts and capping in lymphocytes[1].
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Deoxaphomin | Deoxaphomin is a cytochalasin. Deoxaphomin inhibits Actin filament elongation and reduces the viscosity of polymerized actin filaments. Deoxaphomin induces rounding of fibroblasts, contraction of actin cables, formation of actin-containing hairy structures, and formation of actin-containing cytoplasmic rodlets in fibroblasts. Deoxaphomin inhibits membrane ruffling in fibroblasts and capping in lymphocytes. | |||||||||||||||||||||
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Keywords
