57-66-9
57-66-9
Chemical Structure
Probenecid
- CAS No.: 57-66-9
- Formula:C13H19NO4S
- Molecular Weight:285.36
IUPAC Name: 4-(N,N-dipropylsulfamoyl)benzoic acid
InChIKey: DBABZHXKTCFAPX-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=C(S(=O)(N(CCC)CCC)=O)C=C1
Biological Activity: Probenecid is a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels. Probenecid also inhibits pannexin 1 channels.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Probenecid | 99.94% | Probenecid is a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels. Probenecid also inhibits pannexin 1 channels. | ||||||||||||||||||||
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Probenecid (Standard) | 99.29% | Probenecid (Standard) is the analytical standard of Probenecid. This product is intended for research and analytical applications. Probenecid is a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels. Probenecid also inhibits pannexin 1 channels. | ||||||||||||||||||||
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Probenecid-d14 | 99.54% | Probenecid-d14 is the deuterium labeled Probenecid. Probenecid is a potent and selective agonist of transient receptor potential vanilloid 2 (TRPV2) channels. Probenecid also inhibits pannexin 1 channels. | ||||||||||||||||||||
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Probenecid-d7 | Probenecid-d7 is deuterium-labeled Probenecid (HY-B0545). | |||||||||||||||||||||
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4-Hydroxytolbutamide | 99.69% | 4-Hydroxytolbutamide (Hydroxytolbutamide) is a metabolite of Tolbutamide. 4-Hydroxytolbutamide is metabolized by CYP2C8 and CYP2C9. Tolbutamide is a first generation potassium channel blocker and a sulfonylurea oral antidiabetic. | ||||||||||||||||||||
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INK4C-IN-2 | 98.35% | INK4C-IN-2 is a p18INK4C inhibitor. NK4C-IN-2 promotes hematopoietic stem cells (HSCs) division by inhibiting INK4C and activating CDK4/6, with an ED50 of 5.21 nM. INK4C-IN-2 shows no cytotoxic to normal 32D cells, HSCs, leukemia cell lines and myeloma cell lines. | ||||||||||||||||||||
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NNGH | 98.12% | NNGH is a stromelysin-1 (MMP-3) inhibitor. MMP-3 is both a direct transcriptional target and a necessary contributor of the Wnt/β-catenin signaling pathway. Matrix metalloproteinases (MMPs) play a well-defined role in later stages of tumor progression. | ||||||||||||||||||||
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EG-2184 | 99.50% | EG-2184 is a Pannexin-1 channel inhibitor. EG-2184 can be used in opioid withdrawal related research. | ||||||||||||||||||||
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Tolbutamide | 99.69% | Tolbutamide is an orally active KATP inhibitor. Tolbutamide inhibits cell proliferation, stimulates exocytosis of glucagon and reduces fetal lethality of mice. Tolbutamide can be used in the research of diabete. | ||||||||||||||||||||
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Mafenide propionate | Mafenide propionate is a dual inhibitor of dihydropteroate synthase (Dihydropteroate synthase) and carbonic anhydrase (Carbonic anhydrase). Mafenide propionate disrupts nucleotide biosynthesis by inhibiting the de novo base synthesis pathway, thereby exerting broad-spectrum antibacterial and cytotoxic effects without inducing mutations. Mafenide propionate can be used for wound assessment and promotes the formation of healthy granulation tissue, making it suitable for scenarios such as mesh skin grafting. Mafenide propionate has been widely used in studies on diseases associated with burn wound infections, acute and chronic wounds, blast injuries, open fractures, and necrotizing fasciitis. | |||||||||||||||||||||
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Etebenecid | 99.73% | Etebenecid is a uricosuric agent that also inhibits the renal tubular secretion of penicillin. | ||||||||||||||||||||
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Carboxytolbutamide | 99.02% | Carboxytolbutamide is a toluenesulfonamide metabolite. | ||||||||||||||||||||
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Probenecid sodium | 99.37% | Probenecid sodium is an orally active, blood-brain barrier-permeable Pannexin 1 channel inhibitor. Probenecid sodium exhibits anti-inflammatory, antiviral, and neuroprotective activities. Probenecid sodium can be used in research related to multiple sclerosis, focal cerebral ischemic injury, influenza virus infection, and nephropathy. | ||||||||||||||||||||
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