1 Result for "

811803-05-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "811803-05-1" in MCE Product Catalog:

Cat. No.: HY-13342AS
CAS No.: 2468771-43-7
Purity:  92.56%
Synonyms: YN968D1-d8 free base
Apatinib-d8 (free base) is the deuterium labeled Apatinib free base . Apatinib free base (YN968D1 free base) is an orally bioavailable tyrosine kinase inhibitor, which selectively targets VEGFR-2 (IC50=1 nM). Apatinib free base (YN968D1 free base) is an anti-angiogenic drug for the research of advanced or metastatic gastric cancer. Apatinib free base (YN968D1 free base) potently inhibits Ret, c-Kit and c-Src with IC50s of 13, 429 and 530 nM, respectively. It also inhibits cellular phosphorylation of VEGFR-2, c-kit and PDGFRβ .
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