872511-34-7
872511-34-7
Chemical Structure
Infigratinib
Synonym(s): BGJ-398; NVP-BGJ398
- CAS No.: 872511-34-7
- Formula:C26H31Cl2N7O3
- Molecular Weight:560.48
IUPAC Name: 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea
InChIKey: QADPYRIHXKWUSV-UHFFFAOYSA-N
SMILES: ClC1=C(C(Cl)=C(C=C1OC)OC)NC(N(C2=CC(NC3=CC=C(C=C3)N4CCN(CC4)CC)=NC=N2)C)=O
Biological Activity: Infigratinib (BGJ-398; NVP-BGJ398) is a potent inhibitor of the FGFR family with IC50s of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Infigratinib | 99.82% | Infigratinib (BGJ-398; NVP-BGJ398) is a potent inhibitor of the FGFR family with IC50s of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively. | ||||||||||||||||||||
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Infigratinib (Standard) | 99.40% | Infigratinib (Standard) is the analytical standard of Infigratinib. This product is intended for research and analytical applications. Infigratinib (BGJ-398; NVP-BGJ398) is a potent inhibitor of the FGFR family with IC50s of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively. | ||||||||||||||||||||
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Infigratinib-d3 | 98.90% | Infigratinib-d3 is a deuterated analog of infigratinib. Infigratinib is an effective inhibitor of the FGFR family, with IC50 values of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively. | ||||||||||||||||||||
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