676501-25-0
Chemical Structure
Ondelopran
Synonym(s): LY 2196044
- CAS. Nr.: 676501-25-0
- Formula:C20H24FN3O3
- Molecular Weight:373.42
IUPAC Name: 6-(2-fluoro-4-(((2-(tetrahydro-2H-pyran-4-yl)ethyl)amino)methyl)phenoxy)nicotinamide
InChIKey: QWNDOCKIKKQJNN-UHFFFAOYSA-N
SMILES: FC1=C(OC2=CC=C(C(N)=O)C=N2)C=CC(CNCCC3CCOCC3)=C1
Biological Activity: Ondelopran (LY 2196044) is a non-selective opioid receptor antagonist. Ondelopran inhibits the release of dopamine in the nucleus accumbens induced by alcohol, reduces the rewarding effect of alcohol consumption, and lowers the craving. Ondelopran can be used for alcohol use disorder (AUD)[1].
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Ondelopran | Ondelopran (LY 2196044) is a non-selective opioid receptor antagonist. Ondelopran inhibits the release of dopamine in the nucleus accumbens induced by alcohol, reduces the rewarding effect of alcohol consumption, and lowers the craving. Ondelopran can be used for alcohol use disorder (AUD). | |||||||||||||||||||||
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Keywords
