DPP-8/9 probe-1
DPP-8/9 probe-1 (compound 20) is a fluorescent probe targeting Dipeptidyl Peptidase DPP8/9, which can be selectively labeled and visualized in vitro by fluorescence microscopy Active DPP8/9. DPP-8/9 probe-1 contains a nitrobenzoxadiazole (NBD) tag and has high affinity and selectivity for DPP8/9 over related S9 family members (IC50 of 210 nM and 15 nM, respectively).
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- CAS. Nr.: 3020859-80-4
- Formel: C31H36FN7O7
- Molecular Weight:637.66
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
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DPP-8 210 nM (IC50, [1]) |
DPP-9 15 nM (IC50, [1]) |
DPP-4 .44 μM (IC50, [1]) |
DPP-8/9 probe-1 (compound 20) (10 μM; 30 min) significantly stains and visualizes DPP-8/9 in THP cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:THP-1 monocytes
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Concentration:0.5 μM, 1 μM, 2 μM, 10 μM
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Incubation Time:30 min
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Result:Lower concentrations (0.5 μM, 1 μM and 2 μM) can not be sufficient for in-cell staining
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Chemical Information
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CAS. Nr. 3020859-80-4
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Molecular Weight 637.66
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Formel C31H36FN7O7
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SMILES
O=C(CN[C@@]1(C2)C[C@H]3C[C@@](C[C@@H]2C3)(NC(OCCOCCNC4=CC=C([N+]([O-])=O)C5=NON=C54)=O)C1)N(C6)CC7=C6C=CC(F)=C7
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
DPP-8/9 probe-1 Related Classifications
HY-D2327 Related Classifications
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