3020859-80-4
Chemical Structure
DPP-8/9 probe-1
- CAS No.: 3020859-80-4
- Formula:C31H36FN7O7
- Molecular Weight:637.66
InChIKey: MAIFOHYNLBAWDL-IYTRPCDASA-N
SMILES: O=C(CN[C@@]1(C2)C[C@H]3C[C@@](C[C@@H]2C3)(NC(OCCOCCNC4=CC=C([N+]([O-])=O)C5=NON=C54)=O)C1)N(C6)CC7=C6C=CC(F)=C7
Biological Activity: DPP-8/9 probe-1 (compound 20) is a fluorescent probe targeting Dipeptidyl Peptidase DPP8/9, which can be selectively labeled and visualized in vitro by fluorescence microscopy Active DPP8/9. DPP-8/9 probe-1 contains a nitrobenzoxadiazole (NBD) tag and has high affinity and selectivity for DPP8/9 over related S9 family members (IC50 of 210 nM and 15 nM, respectively)[1].
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DPP-8/9 probe-1 | DPP-8/9 probe-1 (compound 20) is a fluorescent probe targeting Dipeptidyl Peptidase DPP8/9, which can be selectively labeled and visualized in vitro by fluorescence microscopy Active DPP8/9. DPP-8/9 probe-1 contains a nitrobenzoxadiazole (NBD) tag and has high affinity and selectivity for DPP8/9 over related S9 family members (IC50 of 210 nM and 15 nM, respectively). | |||||||||||||||||||||
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Keywords
