Six1 - SIX homeobox 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 114634

Summary

Enables transcription coactivator binding activity. Involved in cellular response to 3,3',5-triiodo-L-thyronine. Located in nucleus. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 23; branchiootorenal syndrome; and nephroblastoma. Orthologous to human SIX1 (SIX homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Six1 Products (1)

mRNA Protein Name
NM_053759.1 NP_446211.1 homeobox protein SIX1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Verweise Source
enables transcription coactivator binding IPI
IPI: Inferred from physical interaction
22197309 RGD
Biological Process GO Annotation Evidence Verweise Source
involved in cellular response to 3,3',5-triiodo-L-thyronine IDA
IDA: Inferred from direct assay
22197309 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

homeobox protein SIX1

  • sine oculis homeobox homolog 1

  • sine oculis-related homeobox 1 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-138657 NCGC00378430 Inhibitor 98.07% Unkown
HY-RS12958 SIX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17696 Six1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24158 Six1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Six1 NCBI NCBI:6495