CNN3 - calponin 3 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 1266

About CNN3

Cytogenetic location: 1p21.3 Genomic coordinates (GRCh38): 1:94,896,957-94,927,110 (from NCBI)

This gene has 7 transcripts (splice variants), 348 orthologues and 5 paralogues. Ubiquitous expression in adrenal (RPKM 52.9), placenta (RPKM 49.2) and 24 other tissues.

Summary

This gene encodes a protein with a markedly acidic C terminus; the basic N-terminus is highly homologous to the N-terminus of a related gene, CNN1. Members of the CNN gene family all contain similar tandemly repeated motifs. This encoded protein is associated with the Cytoskeleton but is not involved in contraction. [provided by RefSeq, Jul 2008]

CNN3 Products (3)

mRNA Protein Name
NM_001286055.2 NP_001272984.1 calponin-3 isoform 2
NM_001286056.2 NP_001272985.1 calponin-3 isoform 3
NM_001839.5 NP_001830.1 calponin-3 isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence Verweise Source
involved in epithelial cell differentiation IEP
IEP: Inferred from expression pattern
21492153 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CNN3 Protein Structure

CH

CH: Calponin homology (CH) domain (29 - 126)

Calponin

Calponin: Calponin family repeat (164 - 189)

Calponin

Calponin: Calponin family repeat (204 - 229)

Calponin

Calponin: Calponin family repeat (243 - 268)

  • 0
  • 100
  • 200
  • 300
  • 329 a.a.
Protein Preferred Names Protein Names

calponin-3

  • calponin 3, acidic

CNN3 Antibodies

Art. -Nr. Produktname Anwendung Reactivity
HY-P84588 CNN3 Antibody (YA4285) WB, IHC-P, ICC/IF, FC, ELISA Human
HY-P84588A CNN3 Antibody (YA4285)(PBS only) WB, IHC-P, ICC/IF, FC, ELISA Human

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS02894 CNN3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20708 Cnn3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27219 Cnn3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus CNN3 VGNC VGNC:61022
Canis familiaris CNN3 VGNC VGNC:39405
Rattus norvegicus CNN3 RGD RGD:71044
Mus musculus CNN3 MGD MGI:1919244
Macaca mulatta CNN3 VGNC VGNC:71278
Others CNN3 NCBI