CALML5 - calmodulin like 5 Gene

Also Known as CLSP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51806

About CALML5

Cytogenetic location: 10p15.1 Genomic coordinates (GRCh38): 10:5,498,697-5,499,570 (from NCBI)

This gene has 1 transcript (splice variant), 239 orthologues and 20 paralogues.

Summary

This gene encodes a novel calcium binding protein expressed in the epidermis and related to the Calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with Transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes. [provided by RefSeq, Jul 2008]

CALML5 Products (1)

mRNA Protein Name
NM_017422.5 NP_059118.2 calmodulin-like protein 5

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CALML5 Protein Structure

EF-hand_7

EF-hand_7: EF-hand domain pair (12 - 72)

EF-hand_7

EF-hand_7: EF-hand domain pair (84 - 142)

  • 0
  • 100
  • 146 a.a.
Protein Preferred Names Protein Names

calmodulin-like protein 5

  • calmodulin-like skin protein

Recombinant CALML5 Proteins

Art. -Nr. Produktname Accession Reinheit
HY-P76760 CALML5 Protein, Human (His) Q9NZT1 (M1-E146) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Schizophrenia 1

  • SCZD1

  • Schizophrenia Susceptibility Locus, Chromosome 5-Related

  • Schizophrenia 1 With Or Without An Affective Disorder
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS01845 CALML5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27619 Calml5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CALML5 VGNC VGNC:56179
Mus musculus CALML5 MGD MGI:1931464
Rattus norvegicus CALML5 RGD RGD:1310047
Macaca mulatta CALML5 VGNC VGNC:70576
Canis familiaris CALML5 VGNC VGNC:38672
Others CALML5 NCBI