Tollip - toll interacting protein Gene

Also Known as 4930403G24Rik; 4931428G15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 54473

Summary

Predicted to enable enzyme binding activity; signaling receptor binding activity; and ubiquitin-like protein binding activity. Involved in interleukin-1-mediated signaling pathway. Part of protein-containing complex. Is expressed in ovary; renal interstitium; renal vasculature; and testis. Orthologous to human TOLLIP (toll interacting protein). [provided by Alliance of Genome Resources, Apr 2022]

Tollip Products (2)

mRNA Protein Name
NM_001347562.1 NP_001334491.1 toll-interacting protein isoform 2
NM_023764.4 NP_076253.1 toll-interacting protein isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
10854325 MGI
Biological Process GO Annotation Evidence Verweise Source
involved in interleukin-1-mediated signaling pathway IDA
IDA: Inferred from direct assay
10854325 MGI
Cellular Component GO Annotation Evidence Verweise Source
part of protein-containing complex IDA
IDA: Inferred from direct assay
10854325 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

toll-interacting protein

Tollip Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
Tollip Q9QZ06 Tom1 Mus musculus O88746
Y2H
14563850
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS14875 TOLLIP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21207 Tollip Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27723 Tollip Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tollip NCBI NCBI:54472