BPIFB1 - BPI fold containing family B member 1 Gene

Also Known as LPLUNC1; C20orf114

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 92747

About BPIFB1

This gene has 3 transcripts (splice variants), 93 orthologues and 12 paralogues. Biased expression in stomach (RPKM 277.8), lung (RPKM 49.9) and 2 other tissues.

Summary

The protein encoded by this gene may be involved in the innate immune response to Bacterial exposure in the mouth, nasal cavities, and lungs. The encoded protein is secreted and is a member of the BPI/LBP/PLUNC protein superfamily. This gene is found with Other members of the superfamily in a cluster on chromosome 20. [provided by RefSeq, Jul 2008]

BPIFB1 Products (1)

mRNA Protein Name
NM_033197.3 NP_149974.2 BPI fold-containing family B member 1 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Verweise Source
involved in innate immune response in mucosa IDA
IDA: Inferred from direct assay
21900486 GOA
involved in negative regulation of toll-like receptor 4 signaling pathway IDA
IDA: Inferred from direct assay
21900486 GOA
Cellular Component GO Annotation Evidence Verweise Source
located in extracellular region IDA
IDA: Inferred from direct assay
20237794 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BPIFB1 Protein Structure

LBP_BPI_CETP

LBP_BPI_CETP: LBP / BPI / CETP family, N-terminal domain (44 - 209)

LBP_BPI_CETP_C

LBP_BPI_CETP_C: LBP / BPI / CETP family, C-terminal domain (363 - 457)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 484 a.a.
Protein Preferred Names Protein Names

BPI fold-containing family B member 1

  • VEMSGP

Recombinant BPIFB1 Proteins

Art. -Nr. Produktname Accession Reinheit
HY-P76178 BPIFB1 Protein, Human (HEK293, His) Q8TDL5 (T22-Q484) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Cholera

  • Vibrio Cholerae Infection

  • Cholera - Vibrio Cholerae

  • Cholera Due To Vibrio Cholerae

  • Vibrio Cholerae

  • Cholera Syndrome

  • Asiatic Cholera

  • Epidemic Cholera
Papillary Cystadenocarcinoma

  • Cystadenocarcinoma, Papillary
Autoimmune Polyendocrine Syndrome Type 1

  • Whitaker Syndrome

  • Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy

  • Autoimmune Polyglandular Syndrome I

  • Polyglandular Type I Autoimmune Syndrome
Chronic Mucocutaneous Candidiasis

  • Candidiasis, Chronic Mucocutaneous

  • Cmc

  • Candidiasis Chronic Mucocutaneous
Cystic Fibrosis

  • Mucoviscidosis

  • CF

  • Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis

  • Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis

  • Cystic Fibrosis Lung Disease, Modifier Of

  • Cystic Fibrosis Of Pancreas

  • Fibrocystic Disease Of Pancreas

  • Cf - [Cystic Fibrosis]

  • Cystic Fibrosis Nos

  • Fibrocystic Disease

  • Fibrocystic Disease Of The Pancreas

  • Mucoviscidosis Of Pancreas

  • Nonproliferative Fibrocystic Disease

  • Pancreatic Cystic Fibrosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS01583 BPIFB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18852 Bpifb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25344 Bpifb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus BPIFB1 VGNC VGNC:26545
Felis catus BPIFB1 VGNC VGNC:60155
Macaca mulatta BPIFB1 VGNC VGNC:107774
Canis familiaris BPIFB1 VGNC VGNC:38507
Mus musculus BPIFB1 MGD MGI:2137431
Rattus norvegicus BPIFB1 RGD RGD:1563047
Others BPIFB1 NCBI