578-66-5
Chemical Structure
8-Aminoquinoline
- CAS No.: 578-66-5
- Formula:C9H8N2
- Molecular Weight:144.18
IUPAC Name: quinolin-8-amine
InChIKey: WREVVZMUNPAPOV-UHFFFAOYSA-N
SMILES: NC1=C2N=CC=CC2=CC=C1
Biological Activity: 8-Aminoquinoline is a chelating ligand and intermediate. 8-Aminoquinoline assists metal-catalyzed direct C (sp2)-H and unactivated C (sp3)-H bond functionalization, copper-mediated C-H/C-H coupling, as well as copper/silver-catalyzed aryl C (sp2)-H amination reactions. 8-Aminoquinoline forms cationic Pt (II) complexes with anti-tumor activity. 8-Aminoquinoline is used in research related to latent malaria, glioblastoma, pancreatic adenocarcinoma, adenocarcinoma and biphasic mesothelioma[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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8-Aminoquinoline | 99.96% | 8-Aminoquinoline is a chelating ligand and intermediate. 8-Aminoquinoline assists metal-catalyzed direct C (sp2)-H and unactivated C (sp3)-H bond functionalization, copper-mediated C-H/C-H coupling, as well as copper/silver-catalyzed aryl C (sp2)-H amination reactions. 8-Aminoquinoline forms cationic Pt (II) complexes with anti-tumor activity. 8-Aminoquinoline is used in research related to latent malaria, glioblastoma, pancreatic adenocarcinoma, adenocarcinoma and biphasic mesothelioma. | ||||||||||||||||||||
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- [1]. Corbet M, et al. 8-Aminoquinoline: a powerful directing group in metal-catalyzed direct functionalization of C-H bonds. Angew Chem Int Ed Engl. 2013 Sep 16;52(38):9896-8.
- [2]. Baird JK, et al. 8-Aminoquinoline Therapy for Latent Malaria. Clinical microbiology reviews. 2019 Sep 18;32(4):e00011-19.
- [3]. Coccè V, et al. In Vitro Activity of Monofunctional Pt-II Complex Based on 8-Aminoquinoline against Human Glioblastoma. Pharmaceutics. 2021 Dec 07;13(12):2101.
Keywords
