GALNT5 - polypeptide N-acetylgalactosaminyltransferase 5 Gene

Also Known as GALNACT5; GALNAC-T5

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 11227

About GALNT5

Cytogenetic location: 2q24.1 Genomic coordinates (GRCh38): 2:157,257,705-157,318,491 (from NCBI)

This gene has 3 transcripts (splice variants), 231 orthologues and 19 paralogues. Biased expression in colon (RPKM 10.1), lung (RPKM 7.0) and 7 other tissues.

Summary

The protein encoded by this gene is a membrane-bound polypeptide N-acetylgalactosaminyltransferase that is found in the Golgi. The encoded protein catalyzes the first step in the mucin-type O-glycosylation of Golgi proteins, transfering an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. [provided by RefSeq, Aug 2016]

GALNT5 Products (2)

mRNA Protein Name
NM_001329868.2 NP_001316797.1 polypeptide N-acetylgalactosaminyltransferase 5 isoform 2
NM_014568.3 NP_055383.1 polypeptide N-acetylgalactosaminyltransferase 5 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables polypeptide N-acetylgalactosaminyltransferase activity IDA
IDA: Inferred from direct assay
10545594 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GALNT5 Protein Structure

Glycos_transf_2

Glycos_transf_2: Glycosyl transferase family 2 (499 - 681)

Ricin_B_lectin

Ricin_B_lectin: Ricin-type beta-trefoil lectin domain (811 - 932)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 940 a.a.
Protein Preferred Names Protein Names

polypeptide N-acetylgalactosaminyltransferase 5

  • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5

Related Diseases

Diseases Alias
Atrial Septal Defect 5

  • ASD5

  • Atrial Heart Septal Defect 5

  • Septal Defect, Atrial, Type 5
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05258 GALNT5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus GALNT5 MGD MGI:2179403
Bos taurus GALNT5 VGNC VGNC:29233
Rattus norvegicus GALNT5 RGD RGD:620361
Canis familiaris GALNT5 VGNC VGNC:53096
Felis catus GALNT5 VGNC VGNC:62452
Macaca mulatta GALNT5 VGNC VGNC:72874
Others GALNT5 NCBI