Kcnab2 - potassium voltage-gated channel, shaker-related subfamily, beta member 2 Gene

Also Known as F5; I2rf5; Kcnb3; kv-beta-2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16498

Summary

Predicted to enable aldo-keto reductase (NADP) activity; Potassium Channel regulator activity; and transmembrane transporter binding activity. Involved in neuromuscular process. Acts upstream of or within hematopoietic progenitor cell differentiation. Located in axon and postsynaptic density. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system; intestine; and sensory organ. Used to study chromosome 1p36 deletion syndrome. Orthologous to human KCNAB2 (potassium voltage-gated channel subfamily A regulatory beta subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Kcnab2 Products (6)

mRNA Protein Name
NM_001252654.2 NP_001239583.1 voltage-gated potassium channel subunit beta-2 isoform 2
NM_001252655.2 NP_001239584.1 voltage-gated potassium channel subunit beta-2 isoform 2
NM_001252656.2 NP_001239585.1 voltage-gated potassium channel subunit beta-2 isoform 1
NM_001355172.1 NP_001342101.1 voltage-gated potassium channel subunit beta-2 isoform 1
NM_001355173.1 NP_001342102.1 voltage-gated potassium channel subunit beta-2 isoform 3
NM_010598.4 NP_034728.2 voltage-gated potassium channel subunit beta-2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15662035 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within hematopoietic progenitor cell differentiation IGI
IGI: Inferred from genetic interaction
24029230 MGI
involved in neuromuscular process IMP
IMP: Inferred from mutant phenotype
11825900 MGI
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
24211303 MGI
is active in axon initial segment IDA
IDA: Inferred from direct assay
18509034 MGI
located in axon terminus IDA
IDA: Inferred from direct assay
11825900 MGI
located in juxtaparanode region of axon IDA
IDA: Inferred from direct assay
11825900 MGI
located in postsynaptic density IDA
IDA: Inferred from direct assay
24211303 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

voltage-gated potassium channel subunit beta-2

  • K(+) channel subunit beta-2

  • neuroimmune protein F5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07104 KCNAB2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kcnab2 NCBI NCBI:8514