Sox17 - SRY-box transcription factor 17 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 312936

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and beta-catenin binding activity. Predicted to be involved in several processes, including circulatory system development; negative regulation of Wnt signaling pathway; and urogenital system development. Predicted to act upstream of or within several processes, including embryonic morphogenesis; endocardium development; and hepaticobiliary system development. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Biomarker of cholangiocarcinoma. Human ortholog(s) of this gene implicated in vesicoureteral reflux. Orthologous to human SOX17 (SRY-box transcription factor 17). [provided by Alliance of Genome Resources, Apr 2022]

Sox17 Products (1)

mRNA Protein Name
NM_001107902.1 NP_001101372.1 transcription factor SOX-17

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables sequence-specific double-stranded DNA binding IMP
IMP: Inferred from mutant phenotype
20204374 RGD
Biological Process GO Annotation Evidence References Source
involved in response to alkaloid IEP
IEP: Inferred from expression pattern
36913491 RGD
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
20204374 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor SOX-17

  • SRY (sex determining region Y)-box 17

  • SRY box 17

  • SRY-box containing gene 17

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-116940 Sm4 Inhibitor 99.01% Unkown
HY-161024 AC1Q3QWB Inhibitor 99.76% Unkown
HY-RS20493 Sox17 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13589 SOX17 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27001 Sox17 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sox17 NCBI NCBI:64321