Mid1 - midline 1 Gene

Also Known as Fxy; Midline1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 54252

Summary

Predicted to enable several functions, including microtubule binding activity; protein homodimerization activity; and ubiquitin protein Ligase binding activity. Predicted to be involved in positive regulation of stress-activated MAPK cascade and protein localization to microtubule. Predicted to act upstream of or within negative regulation of microtubule depolymerization. Predicted to be located in cytoplasm and microtubule. Predicted to colocalize with cytoplasmic microtubule. Human ortholog(s) of this gene implicated in Opitz GBBB syndrome type I. Orthologous to human MID1 (midline 1). [provided by Alliance of Genome Resources, Apr 2022]

Mid1 Products (1)

mRNA Protein Name
NM_022927.1 NP_075216.1 E3 ubiquitin-protein ligase Midline-1
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase Midline-1

  • Finger on X and Y (in rat only on X)

  • RING finger protein Midline-1

  • RING-type E3 ubiquitin transferase Midline-1

  • midline 1 (Opitz/BBB syndrome)

  • tripartite motif-containing protein 18

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-115461 MID-1 Inhibitor 99.67% Phase 2

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08434 MID1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08435 MID1IP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08611 MPG Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18738 Mpg Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18951 Mid1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19281 Mid1ip1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25441 Mid1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25771 Mid1ip1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mid1 NCBI NCBI:4281