NUP37 - nucleoporin 37 Gene

Also Known as p37; MCPH24

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 79023

Summary

Nuclear pore complexes (NPCs) are used for transporting macromolecules between the cytoplasm and the nucleus. NPCs consist of multiple copies of 30 distinct proteins (nucleoporins), which assemble into biochemically-separable subcomplexes. The protein encoded by this gene is part of a subcomplex (Nup107-160) that is required for proper NPC function as well as for normal kinetochore-microtubule interaction and Mitosis. [provided by RefSeq, Dec 2015]

NUP37 Products (1)

mRNA Protein Name
XM_054373197.1 XP_054229172.1 nucleoporin Nup37 isoform X1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15146057 GOA
Cellular Component GO Annotation Evidence References Source
colocalizes with kinetochore IDA
IDA: Inferred from direct assay
15146057 GOA
located in nuclear envelope IDA
IDA: Inferred from direct assay
24315095 GOA
part of nuclear pore outer ring IDA
IDA: Inferred from direct assay
15146057 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nucleoporin Nup37

  • nucleoporin 37kDa

  • nup107-160 subcomplex subunit Nup37

NUP37 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
NUP37 Q8NFH4 SEC13 Homo sapiens P55735
TAP
24981860
Intra
NUP37 Q8NFH4 LAMP2 Homo sapiens P13473-2
Y2H Pooling
32814053
Intra
NUP37 Q8NFH4 LAMP2 Homo sapiens P13473-2
Validated Y2H
32814053
Intra
NUP37 Q8NFH4 LAMP2 Homo sapiens P13473-2
Y2H Array
32814053
Intra
NUP37 Q8NFH4 CASP6 Homo sapiens P55212
Y2H Pooling
32814053
Intra
NUP37 Q8NFH4 CASP6 Homo sapiens P55212
Validated Y2H
32814053
Intra
NUP37 Q8NFH4 CASP6 Homo sapiens P55212
Y2H Array
32814053
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-186241 NuP-3 Inhibitor / Unkown
HY-RS09693 NUP35 Human Pre-designed siRNA Set A Pre-designed Set / Unkown