405168-58-3
405168-58-3
Chemical Structure
CHIR-124
- CAS No.: 405168-58-3
- Formula:C23H22ClN5O
- Molecular Weight:419.91
IUPAC Name: (S)-3-(1H-benzo[d]imidazol-2-yl)-6-chloro-4-(quinuclidin-3-ylamino)quinolin-2(1H)-one
InChIKey: MOVBBVMDHIRCTG-LJQANCHMSA-N
SMILES: ClC1=CC2=C(NC(C(C3=NC4=C(C=CC=C4)N3)=C2N[C@@H]5CN6CCC5CC6)=O)C=C1
Biological Activity: CHIR-124 is a potent and selective Chk1 inhibitor with IC50 of 0.3 nM, and also potently targets PDGFR and FLT3 with IC50s of 6.6 nM and 5.8 nM.
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CHIR-124 | 99.05% | CHIR-124 is a potent and selective Chk1 inhibitor with IC50 of 0.3 nM, and also potently targets PDGFR and FLT3 with IC50s of 6.6 nM and 5.8 nM. | ||||||||||||||||||||
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Keywords
