CY 208-243
Based on 2 publication(s) in Google Scholar
CY 208-243 is a selective dopamine D1 receptor agonist which exhibits antiparkinsonian activity.
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- Pureté: 99.98%
- CAS No.: 100999-26-6
- Formule: C19H18N2
- Masse moléculaire:274.36
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) CY 208-243
MoreVoir tous les produits spécifiques à Isoform Dopamine Receptor
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Activité biologique
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D1 Receptor |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Sprague-Dawley rats (180-200 g)[1]
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Dosage:2.5 mg/kg
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Administration:Subcutaneous
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Result:Prevented the increase of DA release and metabolism induced by the D-1 antagonist.
Chemical Information
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CAS No. 100999-26-6
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Appearance Solid
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Masse moléculaire 274.36
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Formule C19H18N2
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Color White to off-white
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SMILES
CN1[C@@](C2)([H])[C@@](C3=CC=CC=C3C1)([H])C4=CC=CC5=C4C2=CN5
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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Neuron
2024 Jul 25:S0896-6273(24)00494-X. PMID: 39094559 -
Antiviral Res
Discovery of hepatitis B virus subviral particle biogenesis inhibitors from a bioactive compound library. [Abstract]2024 Jul 2:228:105955. PMID: 38964614
Solvant et solubilité
DMSO : 50 mg/mL (182.24 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (275 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Imperato A, et al. CY 208-243, a novel dopamine D-1 receptor agonist, fails to modify dopamine release in freely moving rats. Eur J Pharmacol. 1989 Jan 24;160(1):155-8. [Content Brief]
[2]. Temlett JA, et al. The D-1 dopamine receptor partial agonist, CY 208-243, exhibits antiparkinsonian activity in the MPTP-treated marmoset. Eur J Pharmacol. 1988 Nov 1;156(2):197-206. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6448 mL | 18.2242 mL | 36.4485 mL | 91.1212 mL |
| 5 mM | 0.7290 mL | 3.6448 mL | 7.2897 mL | 18.2242 mL | |
| 10 mM | 0.3645 mL | 1.8224 mL | 3.6448 mL | 9.1121 mL | |
| 15 mM | 0.2430 mL | 1.2149 mL | 2.4299 mL | 6.0747 mL | |
| 20 mM | 0.1822 mL | 0.9112 mL | 1.8224 mL | 4.5561 mL | |
| 25 mM | 0.1458 mL | 0.7290 mL | 1.4579 mL | 3.6448 mL | |
| 30 mM | 0.1215 mL | 0.6075 mL | 1.2149 mL | 3.0374 mL | |
| 40 mM | 0.0911 mL | 0.4556 mL | 0.9112 mL | 2.2780 mL | |
| 50 mM | 0.0729 mL | 0.3645 mL | 0.7290 mL | 1.8224 mL | |
| 60 mM | 0.0607 mL | 0.3037 mL | 0.6075 mL | 1.5187 mL | |
| 80 mM | 0.0456 mL | 0.2278 mL | 0.4556 mL | 1.1390 mL | |
| 100 mM | 0.0364 mL | 0.1822 mL | 0.3645 mL | 0.9112 mL |
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