RAVER1 - ribonucleoprotein, PTB binding 1 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 125950

About RAVER1

Cytogenetic location: 19p13.2 Genomic coordinates (GRCh38): 19:10,316,212-10,333,529 (from NCBI)

This gene has 7 transcripts (splice variants), 194 orthologues and 7 paralogues. Ubiquitous expression in spleen (RPKM 11.2), bone marrow (RPKM 11.0) and 25 other tissues.

Summary

Enables RNA binding activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to be located in cytoplasm. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

RAVER1 Products (2)

mRNA Protein Name
NM_001366174.1 NP_001353103.1 ribonucleoprotein PTB-binding 1 isoform 2
NM_133452.3 NP_597709.3 ribonucleoprotein PTB-binding 1 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
18377426 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RAVER1 Protein Structure

(78 - 132)

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (152 - 220)

(241 - 310)

  • 0
  • 200
  • 400
  • 600
  • 756 a.a.
Protein Preferred Names Protein Names

ribonucleoprotein PTB-binding 1

  • protein raver-1

RAVER1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
RAVER1 Q8IY67 TOB1 Homo sapiens P50616
TAP
18377426
Intra
RAVER1 Q8IY67 GRAP2 Homo sapiens O75791
Y2H Array
32296183
Intra
RAVER1 Q8IY67 GRAP2 Homo sapiens O75791
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS11709 RAVER1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta RAVER1 VGNC VGNC:101482
Rattus norvegicus RAVER1 RGD RGD:1359190
Felis catus RAVER1 VGNC VGNC:102686
Canis familiaris RAVER1 VGNC VGNC:108253
Bos taurus RAVER1 VGNC VGNC:55304
Mus musculus RAVER1 MGD MGI:1919016
Others RAVER1 NCBI