Cux1 - cut-like homeobox 1 Gene

Also Known as CDP; Cux; Cutl1; Cux-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13047

Summary

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and chromatin binding activity. Involved in positive regulation of dendrite morphogenesis. Acts upstream of or within animal organ development and negative regulation of transcription by RNA polymerase II. Located in cytoplasm; neuron projection; and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human CUX1 (cut like homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Cux1 Products (14)

mRNA Protein Name
NM_001291233.2 NP_001278162.1 homeobox protein cut-like 1 isoform c
NM_001291234.2 NP_001278163.1 homeobox protein cut-like 1 isoform d
NM_001291238.2 NP_001278167.1 protein CASP isoform e
NM_001291239.2 NP_001278168.1 protein CASP isoform f
NM_001291240.2 NP_001278169.1 protein CASP isoform g
NM_001405079.1 NP_001392008.1 homeobox protein cut-like 1 isoform h
NM_001405081.1 NP_001392010.1 homeobox protein cut-like 1 isoform i
NM_001405082.1 NP_001392011.1 homeobox protein cut-like 1 isoform j
NM_001405083.1 NP_001392012.1 homeobox protein cut-like 1 isoform k
NM_001405084.1 NP_001392013.1 homeobox protein cut-like 1 isoform l
NM_001405085.1 NP_001392014.1 protein CASP isoform m
NM_001405086.1 NP_001392015.1 protein CASP isoform n
NM_009986.5 NP_034116.3 homeobox protein cut-like 1 isoform a
NM_198602.4 NP_941004.2 protein CASP isoform b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables DNA binding IDA
IDA: Inferred from direct assay
15656993 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
18836447 MGI
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IMP
IMP: Inferred from mutant phenotype
20510857 MGI
enables chromatin binding IDA
IDA: Inferred from direct assay
15994318 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
30726206 MGI
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
1363085 MGI
Biological Process GO Annotation Evidence Références Source
acts upstream of or within inner ear auditory receptor cell differentiation IMP
IMP: Inferred from mutant phenotype
11544187 MGI
acts upstream of or within kidney development IGI
IGI: Inferred from genetic interaction
18829740 MGI
acts upstream of or within lung development IMP
IMP: Inferred from mutant phenotype
11544187 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
1363085 MGI
involved in positive regulation of dendrite morphogenesis IMP
IMP: Inferred from mutant phenotype
20510857 MGI
Cellular Component GO Annotation Evidence Références Source
located in cytoplasm IDA
IDA: Inferred from direct assay
20473291 MGI
located in neuron projection IDA
IDA: Inferred from direct assay
25100583 MGI
located in nucleus IDA
IDA: Inferred from direct assay
1363085 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein CASP

homeobox protein cut-like 1

  • CCAAT displacement protein

  • Cux/CDP homeoprotein

  • cut-like 1

  • homeobox protein cux-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS03369 CUX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19592 Cux1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26088 Cux1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cux1 NCBI NCBI:1523