Eftud2 - elongation factor Tu GTP binding domain containing 2 Gene

Also Known as 116kDa; Snrp116; U5-116kD

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20624

Summary

Predicted to enable GTPase activity and U5 snRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing and mRNA processing. Located in nucleus. Is expressed in several structures, including brain; branchial arch; embryo ectoderm; extraembryonic component; and optic cup. Human ortholog(s) of this gene implicated in esophageal atresia and mandibulofacial dysostosis, Guion-Almeida type. Orthologous to human EFTUD2 (elongation factor Tu GTP binding domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Eftud2 Products (2)

mRNA Protein Name
NM_001109995.1 NP_001103465.1 116 kDa U5 small nuclear ribonucleoprotein component isoform b
NM_011431.3 NP_035561.1 116 kDa U5 small nuclear ribonucleoprotein component isoform a

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
11739632 MGI
Cellular Component GO Annotation Evidence Références Source
located in nucleus IDA
IDA: Inferred from direct assay
11739632 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

116 kDa U5 small nuclear ribonucleoprotein component

  • U5 small nuclear ribonucleoprotein 116 kDa

  • U5 snRNP-specific protein, 116 kDa

  • U5-116 kDa

  • elongation factor Tu GTP-binding domain-containing protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS04203 EFTUD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21120 Eftud2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27639 Eftud2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eftud2 NCBI NCBI:9343