Stx4a - syntaxin 4A (placental) Gene

Also Known as Stx4; Syn4; Syn-4

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20909

Summary

Enables SNARE binding activity. Involved in SNARE complex assembly. Acts upstream of or within cellular response to interferon-gamma. Located in several cellular components, including basolateral plasma membrane; lateral loop; and myelin sheath adaxonal region. Part of SNARE complex. Is expressed in central nervous system; metanephros; and retina. Orthologous to human STX4 (syntaxin 4). [provided by Alliance of Genome Resources, Apr 2022]

Stx4a Products (1)

mRNA Protein Name
NM_009294.3 NP_033320.1 syntaxin-4

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables SNARE binding IPI
IPI: Inferred from physical interaction
17548353 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10394363 MGI
Biological Process GO Annotation Evidence Références Source
involved in SNARE complex assembly IDA
IDA: Inferred from direct assay
21151919 MGI
acts upstream of or within cellular response to type II interferon IDA
IDA: Inferred from direct assay
19144319 MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IDA
IDA: Inferred from direct assay
29874582 MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IMP
IMP: Inferred from mutant phenotype
29874582 MGI
Cellular Component GO Annotation Evidence Références Source
part of SNARE complex IDA
IDA: Inferred from direct assay
18535671 MGI
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
29874582 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: Inferred from mutant phenotype
29874582 MGI
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
18505797 MGI
located in cell surface IDA
IDA: Inferred from direct assay
21151919 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
12832401 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
24895134 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
24895134 MGI
located in lateral loop IDA
IDA: Inferred from direct assay
20237282 MGI
located in myelin sheath adaxonal region IDA
IDA: Inferred from direct assay
20237282 MGI
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
18827011 MGI
located in phagocytic vesicle IDA
IDA: Inferred from direct assay
19144319 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
12832401 MGI
is active in plasma membrane IPI
IPI: Inferred from physical interaction
18535671 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
24895134 MGI
is active in postsynapse IMP
IMP: Inferred from mutant phenotype
24895134 MGI
located in stereocilium IDA
IDA: Inferred from direct assay
36355422 MGI
located in storage vacuole IDA
IDA: Inferred from direct assay
21828338 MGI
located in trans-Golgi network IDA
IDA: Inferred from direct assay
18827011 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

syntaxin-4

Stx4a Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
Stx4 P70452 Stxbp3 Mus musculus Q60770-1
ITC
21193638
Intra
Stx4 P70452 Stxbp3 Mus musculus Q60770-1
X-Ray Diffraction
21193638
Intra
Stx4 P70452 Cenpf Mus musculus Q155P7
Y2H
18827011
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS13984 STX4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown