Tnr - tenascin R Gene

Also Known as TN-R; janusin; restrictin; J1-tenascin

Species: Mus musculus

Gene Type: protein coding
Gene ID: 21960

Summary

Predicted to enable Integrin binding activity. Involved in modulation of chemical synaptic transmission. Acts upstream of or within several processes, including locomotory exploration behavior; modulation of chemical synaptic transmission; and nervous system development. Located in cell surface; membrane raft; and perineuronal net. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is expressed in several structures, including aorta tunica media; brain; heart; urinary system; and ventral grey horn. Orthologous to human TNR (tenascin R). [provided by Alliance of Genome Resources, Apr 2022]

Tnr Products (1)

mRNA Protein Name
NM_022312.3 NP_071707.2 tenascin-R precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Références Source
acts upstream of or within associative learning IMP
IMP: Inferred from mutant phenotype
12882316 MGI
acts upstream of axon extension IDA
IDA: Inferred from direct assay
16831557 MGI
acts upstream of axon extension involved in regeneration IMP
IMP: Inferred from mutant phenotype
16870730 MGI
acts upstream of or within extracellular matrix organization IMP
IMP: Inferred from mutant phenotype
10341229 MGI
acts upstream of or within locomotory exploration behavior IMP
IMP: Inferred from mutant phenotype
14529817 MGI
acts upstream of or within long-term synaptic potentiation IMP
IMP: Inferred from mutant phenotype
11161481 MGI
involved in modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
11377840 MGI
acts upstream of or within modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
11377840 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: Inferred from mutant phenotype
11377840 MGI
acts upstream of or within negative regulation of axon extension IDA
IDA: Inferred from direct assay
16831557 MGI
acts upstream of or within negative regulation of axon extension involved in regeneration IMP
IMP: Inferred from mutant phenotype
16870730 MGI
acts upstream of or within negative regulation of cell-cell adhesion IDA
IDA: Inferred from direct assay
16831557 MGI
acts upstream of or within negative regulation of cell-cell adhesion IMP
IMP: Inferred from mutant phenotype
15034584 MGI
acts upstream of or within negative regulation of neuron projection development IDA
IDA: Inferred from direct assay
9405406 MGI
involved in negative regulation of neuron projection development IDA
IDA: Inferred from direct assay
7527058 MGI
acts upstream of or within negative regulation of synaptic transmission IMP
IMP: Inferred from mutant phenotype
15033179 MGI
acts upstream of or within neuroblast migration IMP
IMP: Inferred from mutant phenotype
15034584 MGI
acts upstream of or within neuromuscular process controlling balance IMP
IMP: Inferred from mutant phenotype
12882316 MGI
acts upstream of or within neuron cell-cell adhesion IMP
IMP: Inferred from mutant phenotype
15034584 MGI
acts upstream of or within positive regulation of synaptic transmission, glutamatergic IMP
IMP: Inferred from mutant phenotype
11161481 MGI
acts upstream of or within positive regulation of transmission of nerve impulse IMP
IMP: Inferred from mutant phenotype
10341229 MGI
involved in regulation of cell adhesion IDA
IDA: Inferred from direct assay
2477380 MGI
involved in regulation of cell differentiation IDA
IDA: Inferred from direct assay
9169525 MGI
involved in regulation of cell migration IDA
IDA: Inferred from direct assay
2477380 MGI
acts upstream of or within synapse organization IMP
IMP: Inferred from mutant phenotype
16262627 MGI
acts upstream of synaptic transmission, glutamatergic IMP
IMP: Inferred from mutant phenotype
11161481 MGI
acts upstream of or within telencephalon cell migration IMP
IMP: Inferred from mutant phenotype
15034584 MGI
Cellular Component GO Annotation Evidence Références Source
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
11377840 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: Inferred from mutant phenotype
11377840 MGI
located in cell surface IDA
IDA: Inferred from direct assay
12056833 MGI
located in collagen-containing extracellular matrix IDA
IDA: Inferred from direct assay
8244531 MGI
located in extracellular matrix IDA
IDA: Inferred from direct assay
7530142 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
11377840 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
11377840 MGI
located in membrane raft IDA
IDA: Inferred from direct assay
12056833 MGI
located in perineuronal net IDA
IDA: Inferred from direct assay
8244531 MGI
part of tenascin complex IPI
IPI: Inferred from physical interaction
2477380 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tenascin-R

  • neural recognition molecule J1-160/180

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS14862 TNR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18902 Tnr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25393 Tnr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnr NCBI NCBI:7143