TNR - tenascin R Gene

Also Known as TN-R; NEDSTO

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 7143

About TNR

Cytogenetic location: 1q25.1 Genomic coordinates (GRCh38): 1:175,315,194-175,743,595 (from NCBI)

This gene has 3 transcripts (splice variants), 209 orthologues, 25 paralogues and is associated with 1 phenotype. Restricted expression toward brain (RPKM 22.5).

Summary

This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The encoded protein is restricted to the central nervous system. The protein may play a role in neurite outgrowth, neural cell adhesion and modulation of Sodium Channel function. It is a constituent of perineuronal nets. [provided by RefSeq, Aug 2013]

TNR Products (2)

mRNA Protein Name
NM_001328635.2 NP_001315564.1 tenascin-R isoform 2
NM_003285.3 NP_003276.3 tenascin-R isoform 1 precursor

TNR Protein Structure

EGF_2

EGF_2: EGF-like domain (204 - 230)

EGF_2

EGF_2: EGF-like domain (300 - 323)

fn3

fn3: Fibronectin type III domain (328 - 399)

fn3

fn3: Fibronectin type III domain (416 - 495)

fn3

fn3: Fibronectin type III domain (507 - 582)

fn3

fn3: Fibronectin type III domain (595 - 672)

fn3

fn3: Fibronectin type III domain (688 - 764)

fn3

fn3: Fibronectin type III domain (776 - 850)

fn3

fn3: Fibronectin type III domain (865 - 942)

fn3

fn3: Fibronectin type III domain (955 - 1027)

fn3

fn3: Fibronectin type III domain (1042 - 1118)

Fibrinogen_C

Fibrinogen_C: Fibrinogen beta and gamma chains, C-terminal globular domain (1135 - 1343)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1358 a.a.
Protein Preferred Names Protein Names

tenascin-R

  • janusin

Related Diseases

Diseases Alias
Neurodevelopmental Disorder, Nonprogressive, With Spasticity And Transient Opisthotonus

  • NEDSTO

  • Neurodevelopmental Disorder, Non-Progressive, With Spasticity And Transient Opisthotonus

  • Non-Progressive Neurodevelopmental Disorder With Spasticity And Transient Opisthotonus
Spasticity
Osteochondritis Dissecans

  • Osteochondritis

  • Ocd

  • Konig Disease
Ehlers-Danlos Syndrome

  • Eds

  • Cutis Hyperelastica

  • Elastic Skin

  • Ehlers-Danlos Syndromes

  • Ed Syndrome

  • Ehlers Danlos Syndrome

  • Ehlers Danlos Disease

  • Eds - [Ehlers-Danlos Syndrome]
Diamond-Blackfan Anemia 1

  • Aase Syndrome

  • DBA1

  • Erythrogenesis Imperfecta

  • Aase-Smith Syndrome Ii

  • Dba

  • Blackfan-Diamond Syndrome

  • Bds

  • Anemia, Congenital Hypoplastic, Of Blackfan And Diamond

  • Anemia, Congenital Erythroid Hypoplastic

  • Red Cell Aplasia, Pure, Hereditary

  • Aregenerative Anemia, Chronic Congenital

  • Rps19-Related Diamond-Blackfan Anemia

  • Chronic Congenital Aregenerative Anemia

  • Congenital Erythroid Hypoplastic Anemia

  • Congenital Hypoplastic Anemia Of Blackfan And Diamond

  • Pure Hereditary Red Cell Aplasia

  • Anemia, Diamond-Blackfan, Type 1

  • Anemia, Diamond-Blackfan

  • Aase Smith Syndrome 2

  • Familial Hypoplastic Anaemia With Malformations

  • Constitutional Pure Red Cell Aplasia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14862 TNR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18902 Tnr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25393 Tnr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris TNR VGNC VGNC:47697
Mus musculus TNR MGD MGI:99516
Macaca mulatta TNR VGNC VGNC:78609
Rattus norvegicus TNR RGD RGD:3886
Bos taurus TNR VGNC VGNC:36202
Felis catus TNR VGNC VGNC:66433
Others TNR NCBI