TNR - tenascin R Gene

Homo sapiens

Also known as TN-R; NEDSTO

Gene ID: 7143 | Gene type: protein coding

About TNR

Cytogenetic location: 1q25.1 Genomic coordinates (GRCh38): 1:175,315,194-175,743,595 (from NCBI)

This gene has 3 transcripts (splice variants), 209 orthologues, 25 paralogues and is associated with 1 phenotype. Restricted expression toward brain (RPKM 22.5).

Summary

This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The encoded protein is restricted to the central nervous system. The protein may play a role in neurite outgrowth, neural cell adhesion and modulation of Sodium Channel function. It is a constituent of perineuronal nets. [provided by RefSeq, Aug 2013]

TNR Products(2)

mRNA	Protein	Name
NM_001328635.2	NP_001315564.1	tenascin-R isoform 2
NM_003285.3	NP_003276.3	tenascin-R isoform 1 precursor

TNR Protein Structure

EGF_2

fn3

Fibrinogen_C

0
300
600
900
1200
1358 a.a.

Protein Preferred Names

Protein Names

tenascin-R

janusin

Related Diseases

Diseases

Alias

Neurodevelopmental Disorder, Nonprogressive, With Spasticity And Transient Opisthotonus

NEDSTO	Neurodevelopmental Disorder, Non-Progressive, With Spasticity And Transient Opisthotonus
Non-Progressive Neurodevelopmental Disorder With Spasticity And Transient Opisthotonus

Spasticity

Osteochondritis Dissecans

Osteochondritis	Ocd
Konig Disease

Ehlers-Danlos Syndrome

Eds	Cutis Hyperelastica
Elastic Skin	Ehlers-Danlos Syndromes
Ed Syndrome	Ehlers Danlos Syndrome
Ehlers Danlos Disease	Eds - [Ehlers-Danlos Syndrome]

Diamond-Blackfan Anemia 1

Aase Syndrome	DBA1
Erythrogenesis Imperfecta	Aase-Smith Syndrome Ii
Dba	Blackfan-Diamond Syndrome
Bds	Anemia, Congenital Hypoplastic, Of Blackfan And Diamond
Anemia, Congenital Erythroid Hypoplastic	Red Cell Aplasia, Pure, Hereditary
Aregenerative Anemia, Chronic Congenital	Rps19-Related Diamond-Blackfan Anemia
Chronic Congenital Aregenerative Anemia	Congenital Erythroid Hypoplastic Anemia
Congenital Hypoplastic Anemia Of Blackfan And Diamond	Pure Hereditary Red Cell Aplasia
Anemia, Diamond-Blackfan, Type 1	Anemia, Diamond-Blackfan
Aase Smith Syndrome 2	Familial Hypoplastic Anaemia With Malformations
Constitutional Pure Red Cell Aplasia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14862	TNR Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	TNR	VGNC	VGNC:47697
Mus musculus	TNR	MGD	MGI:99516
Macaca mulatta	TNR	VGNC	VGNC:78609
Rattus norvegicus	TNR	RGD	RGD:3886
Bos taurus	TNR	VGNC	VGNC:36202
Felis catus	TNR	VGNC	VGNC:66433
Others	TNR	NCBI