Release-retarding Agents

Polycarbophil is an orally active hydrophilic polymer. Polycarbophil achieves bioadhesion through hydrogen bonding between carboxyl groups and mucosal surfaces, and prolongs compound retention time and regulates compound release through swelling properties. Polycarbophil relieves constipation and diarrhea.

Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) is a cosolvent for preparing SDDs of low-solubility agents. Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) exhibits no acute/subchronic/chronic toxicity in rats, with oral activity and LD₅₀ >2.5 g/kg.

Carbomer interpolymer (Carboxy polymethylene (interpolymer)) is an acrylic acid polymer, which can be used as a thickening agent. Carbomer interpolymer provides a stable gel matrix, exhibits good heat, light and microbial contamination resistance. Carbomer interpolymer facilitates the drug release and local application, which can be used in the pharmaceutical industry.

Carbomer homopolymer (Carboxy polymethylene (homopolymer)) is an acrylic acid polymer, which can be used as a thickening agent. Carbomer homopolymer provides a stable gel matrix, exhibits good heat, light and microbial contamination resistance. Carbomer homopolymer facilitates the drug release and local application, which can be used in the pharmaceutical industry.

Carbomer copolymer can be used as an excipient, such as Bioadhesives, emulsifiers, release modifiers, suspending agents, tablet binders, viscosity enhancers, etc. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs.