Birc6 - baculoviral IAP repeat-containing 6 Gene

Also Known as Bruce; mKIAA1289; A430032G04Rik; A430040A19Rik; D630005A10Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12211

Summary

Enables ubiquitin conjugating enzyme activity. Involved in placenta development. Acts upstream of or within embryonic placenta development; negative regulation of apoptotic process; and positive regulation of cell population proliferation. Located in membrane. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human BIRC6 (baculoviral IAP repeat containing 6). [provided by Alliance of Genome Resources, Apr 2022]

Birc6 Products (2)

mRNA Protein Name
NM_001402769.1 NP_001389698.1 baculoviral IAP repeat-containing protein 6 isoform 2
NM_007566.3 NP_031592.3 baculoviral IAP repeat-containing protein 6

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15314180 MGI
enables ubiquitin conjugating enzyme activity IDA
IDA: Inferred from direct assay
9628897 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of cell population proliferation IMP
IMP: Inferred from mutant phenotype
15887267 MGI
acts upstream of or within labyrinthine layer development IMP
IMP: Inferred from mutant phenotype
15485903 MGI
acts upstream of or within negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
15300255 MGI
involved in placenta development IMP
IMP: Inferred from mutant phenotype
15485903 MGI
acts upstream of or within positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
15887267 MGI
acts upstream of or within regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
15485903 MGI
acts upstream of or within spongiotrophoblast layer development IMP
IMP: Inferred from mutant phenotype
15485903 MGI
Cellular Component GO Annotation Evidence References Source
located in membrane IDA
IDA: Inferred from direct assay
9628897 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

baculoviral IAP repeat-containing protein 6

  • BIR repeat-containing ubiquitin-conjugating enzyme

  • RING-type E3 ubiquitin transferase BIRC6

  • apollon

  • baculovirus inhibitor of apoptosis repeat containing ubiquitin-conjugating enzyme

  • baculovirus inhibitor of apoptosis repeat containing ubiquitin-conjug

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01514 BIRC6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20370 Birc6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26880 Birc6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Birc6 NCBI NCBI:57448