Stra6 - stimulated by retinoic acid gene 6 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20897

Summary

Predicted to enable retinol transmembrane transporter activity. Acts upstream of or within positive regulation of receptor signaling pathway via JAK-STAT and retinol transport. Located in plasma membrane. Is expressed in several structures, including central nervous system; embryo mesenchyme; extraembryonic component; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in syndromic microphthalmia 9. Orthologous to human STRA6 (signaling receptor and transporter of retinol STRA6). [provided by Alliance of Genome Resources, Apr 2022]

Stra6 Products (4)

mRNA Protein Name
NM_001162475.1 NP_001155947.1 receptor for retinol uptake STRA6
NM_001162476.1 NP_001155948.1 receptor for retinol uptake STRA6
NM_001162479.1 NP_001155951.1 receptor for retinol uptake STRA6
NM_009291.2 NP_033317.2 receptor for retinol uptake STRA6

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23105095 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within establishment of localization in cell IMP
IMP: Inferred from mutant phenotype
23839944 MGI
acts upstream of or within positive regulation of receptor signaling pathway via JAK-STAT IMP
IMP: Inferred from mutant phenotype
23839944 MGI
acts upstream of or within retinol transport IGI
IGI: Inferred from genetic interaction
23105095 MGI
acts upstream of or within retinol transport IMP
IMP: Inferred from mutant phenotype
23839944 MGI
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
23105095 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

receptor for retinol uptake STRA6

  • retinoic acid-responsive protein

  • retinol-binding protein receptor STRA6

  • stimulated by retinoic acid gene 6 protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13957 STRA6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21059 Stra6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27576 Stra6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Stra6 NCBI NCBI:64220