Bccip - BRCA2 and CDKN1A interacting protein Gene

Also Known as TOK-1; 1110013J05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66165

Summary

Predicted to enable kinase regulator activity and tubulin binding activity. Involved in cellular response to DNA damage stimulus; microtubule anchoring; and mitotic spindle organization. Located in centrosome and mitotic spindle pole. Is expressed in several structures, including axial musculature; brain ventricular layer; orbito-sphenoid; submandibular gland primordium; and thymus primordium. Orthologous to human BCCIP (BRCA2 and CDKN1A interacting protein). [provided by Alliance of Genome Resources, Apr 2022]

Bccip Products (1)

mRNA Protein Name
NM_025392.2 NP_079668.2 BRCA2 and CDKN1A-interacting protein

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in DNA damage response IMP
IMP: Inferred from mutant phenotype
21966279 MGI
involved in microtubule anchoring IMP
IMP: Inferred from mutant phenotype
28394342 MGI
involved in microtubule cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
28394342 MGI
involved in mitotic spindle organization IMP
IMP: Inferred from mutant phenotype
28394342 MGI
Cellular Component GO Annotation Evidence References Source
located in centrosome IDA
IDA: Inferred from direct assay
28394342 MGI
located in mitotic spindle pole IDA
IDA: Inferred from direct assay
28394342 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

BRCA2 and CDKN1A-interacting protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01404 BCCIP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19657 Bccip Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26150 Bccip Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bccip NCBI NCBI:56647