1. Antibody-drug Conjugate/ADC Related
  2. Drug-Linker Conjugates for ADC
  3. DGN549-C

DGN549-C 

Cat. No.: HY-136297
Handling Instructions

DGN549-C consists a cleavable ADC linker valine-alanine (va) and PBD dimer. DGN549 is a novel DNA-alkylating cytotoxic payload and can be used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

DGN549-C Chemical Structure

DGN549-C Chemical Structure

CAS No. : 2058075-34-4

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Description

DGN549-C consists a cleavable ADC linker valine-alanine (va) and PBD dimer. DGN549 is a novel DNA-alkylating cytotoxic payload and can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target[1]

Traditional Cytotoxic Agents

 

Molecular Weight

1100.18

Formula

C₆₀H₆₁N₉O₁₂

CAS No.

2058075-34-4

SMILES

O=C1N2[[email protected]](CC3=C2C=CC=C3)([H])C=NC4=C1C=C(OC)C(OCC5=CC(COC6=C(OC)C=C(C(N(C(C=CC=C7)=C7C8)[[email protected]]8([H])CN9)=O)C9=C6)=CC(NC([[email protected]](C)NC([[email protected]](C)NC(CCCCC(NCCN%10C(C=CC%10=O)=O)=O)=O)=O)=O)=C5)=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

DGN549-CDrug-Linker Conjugates for ADCInhibitorinhibitorinhibit

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