2. Antibody-drug Conjugate/ADC Related
  3. Drug-Linker Conjugates for ADC
  4. DGN549-C

DGN549-C consists a cleavable ADC linker valine-alanine (va) and PBD dimer. DGN549 is a novel DNA-alkylating cytotoxic payload and can be used in the synthesis of antibody-agent conjugates (ADCs).

For research use only. We do not sell to patients.

DGN549-C Chemical Structure

DGN549-C Chemical Structure

CAS No. : 2058075-34-4

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DGN549-C Related Antibodies

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Description

DGN549-C consists a cleavable ADC linker valine-alanine (va) and PBD dimer. DGN549 is a novel DNA-alkylating cytotoxic payload and can be used in the synthesis of antibody-agent conjugates (ADCs)[1].

IC50 & Target[1]

Traditional Cytotoxic Agents

 

Molecular Weight

1100.18

Formula

C60H61N9O12
CAS No.
SMILES

O=C1N2[C@](CC3=C2C=CC=C3)([H])C=NC4=C1C=C(OC)C(OCC5=CC(COC6=C(OC)C=C(C(N(C(C=CC=C7)=C7C8)[C@]8([H])CN9)=O)C9=C6)=CC(NC([C@H](C)NC([C@H](C)NC(CCCCC(NCCN%10C(C=CC%10=O)=O)=O)=O)=O)=O)=C5)=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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DGN549-C Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DGN549-C2058075-34-4Drug-Linker Conjugates for ADCInhibitorinhibitorinhibit

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