IFI44L - interferon induced protein 44 like Gene

Also Known as GS3686; TLDC5B; C1orf29

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10964

About IFI44L

Cytogenetic location: 1p31.1 Genomic coordinates (GRCh38): 1:78,620,448-78,646,145 (from NCBI)

This gene has 18 transcripts (splice variants), 1015 orthologues and 1 paralogue. Broad expression in spleen (RPKM 16.8), bone marrow (RPKM 13.1) and 23 other tissues.

Summary

Predicted to enable GTP binding activity. Involved in defense response to virus. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

IFI44L Products (6)

mRNA Protein Name
NM_001375646.1 NP_001362575.1 interferon-induced protein 44-like isoform 1
NM_001375647.1 NP_001362576.1 interferon-induced protein 44-like isoform 2
NM_001375648.1 NP_001362577.1 interferon-induced protein 44-like isoform 2
NM_001375649.1 NP_001362578.1 interferon-induced protein 44-like isoform 2
NM_001375650.1 NP_001362579.1 interferon-induced protein 44-like isoform 2
NM_006820.4 NP_006811.2 interferon-induced protein 44-like isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in defense response to virus IDA
IDA: Inferred from direct assay
21478870 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interferon-induced protein 44-like

Related Diseases

Diseases Alias
Multisystem Inflammatory Syndrome In Children

  • Mis-C

  • Multisystem Inflammatory Disorder In Children And Adolescents

  • Paediatric Inflammatory Multisystemic Syndrome

  • Mic
Immunodeficiency 38 With Basal Ganglia Calcification

  • Mendelian Susceptibility To Mycobacterial Diseases Due To Complete Isg15 Deficiency

  • IMD38

  • Immunodeficiency 38, Mycobacteriosis, Autosomal Recessive

  • Immunodeficiency 38

  • Isg15 Deficiency, Autosomal Recessive

  • Immunodeficiency 38, With Basal Ganglia Calcification

  • Autosomal Recessive Isg15 Deficiency

  • Msmd Due To Complete Isg15 Deficiency

  • Immunodeficiency, Type 38
Potocki-Shaffer Syndrome

  • Proximal 11p Deletion Syndrome

  • Chromosome 11p11.2 Deletion Syndrome

  • Pss

  • 11p11.2 Deletion

  • P11pds

  • Defect11 Syndrome

  • Deletion Of Chromosome 11p11.2

  • POSHS
Lymph Node Tuberculosis

  • King'S Evil

  • Scrofula

  • Tuberculous Adenitis

  • Tuberculous Lymphadenopathy

  • Tuberculosis, Lymph Node
Childhood Type Dermatomyositis

  • Juvenile Dermatomyositis

  • Juvenile Dm

  • Childhood Dermatomyositis

  • Amyopathic Dermatomyositis

  • Adm

  • Dermatomyositis Sine Myositis

  • Dermatomyositis, Childhood Type
Aicardi-Goutieres Syndrome

  • Aicardi Goutieres Syndrome

  • Cree Encephalitis

  • Aicardi-Goutières Syndrome

  • Encephalopathy With Basal Ganglia Calcification

  • Ags

  • Encephalopathy With Intracranial Calcification And Chronic Lymphocytosis Of Cerebrospinal Fluid

  • Pseudotoxoplasmosis Syndrome

  • Encephalopathy, Familial Infantile, With Calcification Of Basal Ganglia And Chronic Cerebrospinal Fluid Lymphocytosis

  • Familial Infantile Encephalopathy With Intracranial Calcification And Chronic Cerebrospinal Fluid Lymphocytosis

  • Aicardi-Goutieres Syndrome 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06557 IFI44L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21868 Ifi44l Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28385 Ifi44l Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus IFI44L VGNC VGNC:30046
Rattus norvegicus IFI44L RGD RGD:1595861
Macaca mulatta IFI44L VGNC VGNC:73407
Felis catus IFI44L VGNC VGNC:62874
Mus musculus IFI44L MGD MGI:95975
Canis familiaris IFI44L VGNC VGNC:41874
Others IFI44L NCBI