Map3k11 - mitogen-activated protein kinase kinase kinase 11 Gene

Also Known as Mlk3; PTK1; SPRK; 2610017K16Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 26403

Summary

Predicted to enable several functions, including ATP binding activity; JUN kinase kinase kinase activity; and enzyme binding activity. Predicted to be involved in several processes, including JNK cascade; positive regulation of MAPK cascade; and positive regulation of neuron apoptotic process. Predicted to act upstream of or within phosphorylation. Predicted to be located in microtubule. Predicted to be active in centrosome. Is expressed in blood vessel and brain. Orthologous to human MAP3K11 (mitogen-activated protein kinase kinase kinase 11). [provided by Alliance of Genome Resources, Apr 2022]

Map3k11 Products (1)

mRNA Protein Name
NM_022012.3 NP_071295.2 mitogen-activated protein kinase kinase kinase 11

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15767678 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitogen-activated protein kinase kinase kinase 11

  • mixed lineage kinase 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08048 MAP3K11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20638 Map3k11 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27147 Map3k11 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Map3k11 NCBI NCBI:4296