RANBP6 - RAN binding protein 6 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 26953

About RANBP6

This gene has 3 transcripts (splice variants), 59 orthologues and 5 paralogues. Ubiquitous expression in bone marrow (RPKM 13.1), brain (RPKM 11.6) and 25 other tissues.

Summary

Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Predicted to be involved in protein import into nucleus. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

RANBP6 Products (3)

mRNA Protein Name
NM_001243202.2 NP_001230131.1 ran-binding protein 6 isoform 2
NM_001243203.2 NP_001230132.1 ran-binding protein 6 isoform 3
NM_012416.4 NP_036548.1 ran-binding protein 6 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22190034 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RANBP6 Protein Structure

HEAT_2

HEAT_2: HEAT repeats (371 - 474)

HEAT

HEAT: HEAT repeat (920 - 942)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1105 a.a.
Protein Preferred Names Protein Names

ran-binding protein 6

  • Ran-GTP binding protein

RANBP6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
RANBP6 O60518 q76353_9hiv1 Human immunodeficiency virus Q76353
Pull Down
22190034
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Primary Mediastinal B-Cell Lymphoma

  • Large Cell Lymphoma Of The Mediastinum

  • Mediastinal Diffuse Large-Cell Lymphoma With Sclerosis

  • Primary Mediastinal Clear Cell Lymphoma Of B-Cell Type
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11648 RANBP6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus RANBP6 VGNC VGNC:50254
Rattus norvegicus RANBP6 RGD RGD:1305165
Mus musculus RANBP6 MGD MGI:2683212
Others RANBP6 NCBI