ELFN1 - extracellular leucine rich repeat and fibronectin type III domain containing 1 Gene

Also Known as PPP1R28

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 392617

About ELFN1

Cytogenetic location: 7p22.3 Genomic coordinates (GRCh38): 7:1,666,064-1,747,946 (from NCBI)

This gene has 4 transcripts (splice variants), 247 orthologues, 22 paralogues and is associated with 1 phenotype. Broad expression in liver (RPKM 1.3), kidney (RPKM 0.9) and 14 other tissues.

Summary

Predicted to enable protein Phosphatase Inhibitor activity. Predicted to be involved in synapse organization. Predicted to be located in dendrite and excitatory synapse. Predicted to be active in extracellular matrix and extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

ELFN1 Products (3)

mRNA Protein Name
NM_001128636.4 NP_001122108.1 protein ELFN1 precursor
NM_001394187.1 NP_001381116.1 protein ELFN1 precursor
NM_001394188.1 NP_001381117.1 protein ELFN1 precursor

ELFN1 Protein Structure

LRR_8

LRR_8: Leucine rich repeat (109 - 168)

  • 0
  • 200
  • 400
  • 600
  • 828 a.a.
Protein Preferred Names Protein Names

protein ELFN1

  • extracellular leucine-rich repeat and fibronectin type III containing 1

Related Diseases

Diseases Alias
Congenital Stationary Night Blindness

  • Night Blindness, Congenital Stationary

  • Congenital Essential Nyctalopia

  • Oguchi Disease

  • Blindness, Night, Stationary, Congenital
Attention Deficit-Hyperactivity Disorder

  • Attention Deficit Hyperactivity Disorder

  • ADHD

  • Attention Deficit Disorder

  • Attention Deficit-Hyperactivity Disorder, Susceptibility To

  • Attention Deficit Disorder With Hyperactivity

  • Hyperkinetic Disorder

  • Hyperactivity Of Childhood

  • Attention-Deficit/Hyperactivity Disorder

  • Add

  • Addh

  • Attention Deficit

  • Attention Deficit Disorder Of Childhood With Hyperactivity

  • Attention Deficit Disorder With Hyperactivity Syndrome

  • Hyperkinetic Syndrome

  • Attention-Deficit Hyperactivity Disorder

  • Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type

  • Disturbance Of Activity And Attention

  • Disorder Of Activity And Attention

  • Adhd - [Attention Deficit Hyperactivity Disorder]

  • Hyperkinetic Disorders

  • Disorder Of Activity And Attention With Hyperkinesia

  • Attention Deficit Syndrome With Hyperactivity
Cone-Rod Dystrophy 2

  • Cone-Rod Dystrophy

  • CORD2

  • Cone-Rod Retinal Dystrophy

  • Rcrd2

  • Cone-Rod Retinal Dystrophy 2

  • Crd2

  • Cord

  • Crd

  • Retinal Cone-Rod Dystrophy

  • Cone-Rod Retinal Dystrophy-2

  • Retinal Cone-Rod Dystrophy 2

  • Tapetoretinal Degeneration

  • Cone-Rod Degeneration

  • Cone Rod Dystrophy

  • Dystrophy, Cone-Rod

  • Dystrophy, Cone-Rod, Type 2

  • Retinitis Pigmentosa

  • Retinitis Pigmentosa 2

  • Progressive Cone-Rod Dystrophy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04303 ELFN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22483 Elfn1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29006 Elfn1 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ELFN1 RGD RGD:1308787
Macaca mulatta ELFN1 VGNC VGNC:72204
Bos taurus ELFN1 VGNC VGNC:28431
Mus musculus ELFN1 MGD MGI:2442479
Felis catus ELFN1 VGNC VGNC:80569
Others ELFN1 NCBI