Antibiotic Inhibitor
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Aculeacin A
0 ImagesReferencia número: HY-W747508No. CAS: 58814-86-1Aculeacin A is a β-1,3-glucan synthase inhibitor. Aculeacin A is an antifungal antibiotic. Aculeacin A inhibits cell wall glucan synthesis in growing yeast cells, induces cell lysis, osmotic fragility, cell aggregation and abnormal cell morphology, without affecting the synthesis of proteins, nucleic acids or mannan. Aculeacin A acts only on growing yeast cells and has a narrow antifungal spectrum, mainly targeting Candida and Torulopsis species. Aculeacin A shows reduced activity in human serum and exhibits a paradoxical dose-response pattern. Aculeacin A has an inoculum effect against some Candida albicans strains, and its activity is pH-stable. Aculeacin A can be used in studies of fungal infections, such as those caused by Candida, Torulopsis and other species.
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S-2,3-Dicarboxyaziridine
0 ImagesReferencia número: HY-N15080No. CAS: 57528-68-4S-2,3-Dicarboxyaziridine, a metabolite that can be isolated from a streptomyces, possesses anti-bacterial activity.
