SUGP1 - SURP and G-patch domain containing 1 Gene

Also Known as RBP; SF4; F23858

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57794

About SUGP1

Cytogenetic location: 19p13.11 Genomic coordinates (GRCh38): 19:19,276,033-19,320,509 (from NCBI)

This gene has 15 transcripts (splice variants), 91 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 17.9), spleen (RPKM 9.9) and 25 other tissues.

Summary

SF4 is a member of the SURP family of splicing factors.[supplied by OMIM, Sep 2003]

SUGP1 Products (1)

mRNA Protein Name
NM_172231.4 NP_757386.2 SURP and G-patch domain-containing protein 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21988832 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SUGP1 Protein Structure

Surp

Surp: Surp module (189 - 242)

Surp

Surp: Surp module (264 - 317)

G-patch

G-patch: G-patch domain (563 - 606)

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  • 645 a.a.
Protein Preferred Names Protein Names

SURP and G-patch domain-containing protein 1

  • RNA-binding protein RBP

SUGP1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SUGP1 Q8IWZ8 DHX15 Homo sapiens O43143
Anti Tag CoIP
22365833
Intra
SUGP1 Q8IWZ8 RBM10 Homo sapiens P98175
Anti Tag CoIP
22365833
Intra
SUGP1 Q8IWZ8 RBM17 Homo sapiens Q96I25
Anti Tag CoIP
22365833
Intra
SUGP1 Q8IWZ8 RBM17 Homo sapiens Q96I25
Y2H
22365833
Intra
SUGP1 Q8IWZ8 U2AF2 Homo sapiens P26368
Y2H
22365833
Intra
SUGP1 Q8IWZ8 U2AF2 Homo sapiens P26368
Y2H
21988832
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14009 SUGP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SUGP1 VGNC VGNC:35463
Rattus norvegicus SUGP1 RGD RGD:1310496
Canis familiaris SUGP1 VGNC VGNC:46972
Felis catus SUGP1 VGNC VGNC:65830
Macaca mulatta SUGP1 VGNC VGNC:97833
Mus musculus SUGP1 MGD MGI:1917866
Others SUGP1 NCBI