Copy Link Print Information

Donzakimig

(Synonyms: UCB-1381)
Revisión del cliente

Based on 1 Customer Validation

Donzakimig is a trispecific anti-IL-13/IL-22/HSA antibody. Donzakimig adopts a Fab-scFv-scFv structural format (without an Fc region), in which the Fab domain is linked to the scFv domains via a S (G4S)2 linker. Donzakimig binds to and inhibits the activities of IL-13 and IL-22, thereby blocking the signal transduction of these two cytokines. Donzakimig can extend its serum half-life by binding to human serum albumin, enhancing its in vivo stability and achieving long-acting efficacy. Donzakimig can be used in research on moderate-to-severe atopic dermatitis, moderate-to-severe asthma (especially eosinophilic type), psoriasis, inflammatory bowel disease, and other conditions.

Para uso exclusivo en investigación. No vendemos a pacientes.

  • Pureza: 98.67%
  • No. CAS: 2765066-99-5
  • Peso molecular:101.048 kDa
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Donzakimig
  • Experimental Validation Results for Donzakimig
  • Experimental Validation Results for Donzakimig
  • Experimental Validation Results for Donzakimig
  • Donzakimig Chemical Structure
    Donzakimig Chemical Structure
No. CAS: 2765066-99-5
Tamaño
Precio
Stock
Cantidad
Amount: USD 0.00
Please select quantity
or
or

* Seleccione Cantidad antes de agregar artículos.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Donzakimig Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Encuentre su distribuidor local Your local distributor: Hycultec GmbHHycultec
  • Actividad biológica
  • Chemical Information
  • Pureza y Documentación
  • Referencias
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

Ver todos los productos específicos de isoformas Interleukin Related

More
Keywords
100 mg

Obtener un presupuesto En stock

Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Inicie sesiòn
Registrar
Sign in to MedChemExpress
Registrar una cuenta nueva

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    Fab-G1_kappa-scFv-heavy-kappa

  • 1/16

    Immobilized Human IL-22 Protein, His Tag can bind Donzakimig. The EC50 for this effect is 232 ng/mL.

  • 1/16

    Immobilized Human ALB-His-Q Tag can bind Donzakimig. The EC50 for this effect is 145.8 ng/mL.

  • 1/16

    Immobilized Human IL-13 Protein, His Tag can bind Donzakimig. The EC50 for this effect is 287.2 ng/mL.

  • Donzakimig Chemical Structure
    1/16
  • Donzakimig
  • Immobilized Human IL-22 Protein, His Tag can bind Donzakimig. The EC50 for this effect is 232 ng/mL.
  • Immobilized Human ALB-His-Q Tag can bind Donzakimig. The EC50 for this effect is 145.8 ng/mL.
  • Immobilized Human IL-13 Protein, His Tag can bind Donzakimig. The EC50 for this effect is 287.2 ng/mL.
  • Fab-G1_kappa-scFv-heavy-kappa