Trdn - triadin Gene

Also Known as TDN; EG432451; 2310045H21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 76757

Summary

Predicted to enable transmembrane transporter binding activity. Involved in heart contraction. Acts upstream of or within release of sequestered calcium ion into cytosol by sarcoplasmic reticulum and response to bacterium. Predicted to be located in cytosol and sarcoplasmic reticulum. Predicted to be part of Calcium Channel complex and junctional membrane complex. Predicted to be active in junctional sarcoplasmic reticulum membrane and plasma membrane. Is expressed in embryo and heart. Human ortholog(s) of this gene implicated in catecholaminergic polymorphic ventricular tachycardia and catecholaminergic polymorphic ventricular tachycardia 5. Orthologous to human TRDN (triadin). [provided by Alliance of Genome Resources, Apr 2022]

Trdn Products (3)

mRNA Protein Name
NM_001364696.1 NP_001351625.1 triadin isoform 2
NM_001364697.1 NP_001351626.1 triadin isoform 3
NM_029726.2 NP_084002.2 triadin isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Referencias Source
enables protein binding IPI
IPI: Inferred from physical interaction
24125847 MGI
Biological Process GO Annotation Evidence Referencias Source
acts upstream of or within establishment of localization in cell IMP
IMP: Inferred from mutant phenotype
19383796 MGI
acts upstream of or within heart contraction IMP
IMP: Inferred from mutant phenotype
19383796 MGI
involved in heart contraction IMP
IMP: Inferred from mutant phenotype
22422768 MGI
acts upstream of or within release of sequestered calcium ion into cytosol by sarcoplasmic reticulum IMP
IMP: Inferred from mutant phenotype
19383796 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

triadin

  • cardiac triadin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-RS15000 TRDN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21448 Trdn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27966 Trdn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trdn NCBI NCBI:10345