TSC22D2 - TSC22 domain family member 2 Gene

Also Known as TILZ4a; TILZ4b; TILZ4c

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9819

About TSC22D2

Cytogenetic location: 3q25.1 Genomic coordinates (GRCh38): 3:150,408,298-150,466,422 (from NCBI)

This gene has 7 transcripts (splice variants), 233 orthologues and 3 paralogues. Ubiquitous expression in bone marrow (RPKM 8.5), gall bladder (RPKM 7.8) and 25 other tissues.

Summary

Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within response to osmotic stress. [provided by Alliance of Genome Resources, Apr 2022]

TSC22D2 Products (2)

mRNA Protein Name
NM_001303264.2 NP_001290193.1 TSC22 domain family protein 2 isoform 2
NM_014779.4 NP_055594.1 TSC22 domain family protein 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Referencias Source
enables protein binding IPI
IPI: Inferred from physical interaction
22510880 GOA
Biological Process GO Annotation Evidence Referencias Source
involved in negative regulation of cell cycle IMP
IMP: Inferred from mutant phenotype
27573352 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TSC22D2 Protein Structure

TSC22

TSC22: TSC-22/dip/bun family (694 - 751)

  • 0
  • 200
  • 400
  • 600
  • 780 a.a.
Protein Preferred Names Protein Names

TSC22 domain family protein 2

  • TSC22 domain family 2

Related Diseases

Diseases Alias
Keratomalacia

  • Vitamin A Deficiency

  • Night Blindness

  • Retinol Deficiency

  • Xerotic Keratitis

  • VAD

  • Vitamin A

  • Hypovitaminosis A

  • Bitot Spots

  • Bitot Spots In The Young Child

  • Conjunctival Xerosis With Bitot'S Spots

  • Vitamin A Deficiency With Cornea Xerosis

  • Vitamin A Deficiency With Cornea Ulceration Or Xerosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-RS15134 TSC22D2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus TSC22D2 RGD RGD:1593169
Bos taurus TSC22D2 VGNC VGNC:36409
Canis familiaris TSC22D2 VGNC VGNC:47893
Mus musculus TSC22D2 MGD MGI:1919283
Felis catus TSC22D2 VGNC VGNC:66608
Macaca mulatta TSC22D2 VGNC VGNC:110322
Others TSC22D2 NCBI