Multitarget AD-IN-5
Multitarget AD-IN-5 (Compound 20), 9-Aminoacridine (HY-B1422) derivative, is a neuroprotective agent. Multitarget AD-IN-5 shows IC50 values of 0.614, 0.448, 3.73 and 1.55 μM for hAChE, hBChE, hMAO-A and hMAO-B. Multitarget AD-IN-5 can reduce length and diameter of Aβ42 fibers, and decrease the number of fibers per unit area. Multitarget AD-IN-5 can be used for research of Alzheimer's disease.
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- Fòrmula: C21H15Cl3N2O
- Peso molecular:417.72
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Actividad biológica
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Chemical Information
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Actividad biológica
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hAChE 0.614 μM (IC50) |
hBCHE 0.448 μM (IC50) |
hMAO-A 3.73 μM (IC50) |
hMAO-B 1.55 μM (IC50) |
Multitarget AD-IN-5 shows a CC50 of 95 μM for SH-SY5Ycells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Peso molecular 417.72
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Fòrmula C21H15Cl3N2O
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SMILES
COC1=CC2=C(NCC3=CC=C(Cl)C(Cl)=C3)C4=CC=C(Cl)C=C4N=C2C=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Multitarget AD-IN-5 Related Classifications
HY-181041 Related Classifications
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