Ldlrap1 - low density lipoprotein receptor adaptor protein 1 Gene

Also Known as Arh; ARH2; Arh1; FHCB1; FHCB2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 100017

Summary

Enables amyloid-beta binding activity. Acts upstream of or within Cholesterol homeostasis. Located in early endosome and neurofilament. Is expressed in naris; nasal cavity respiratory epithelium; olfactory epithelium; parietal endoderm; and yolk sac endoderm. Used to study autosomal recessive hypercholesterolemia. Human ortholog(s) of this gene implicated in autosomal recessive hypercholesterolemia. Orthologous to human LDLRAP1 (low density lipoprotein receptor adaptor protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Ldlrap1 Products (1)

mRNA Protein Name
NM_145554.2 NP_663529.2 low density lipoprotein receptor adapter protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables amyloid-beta binding IPI
IPI: Inferred from physical interaction
17727637 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12746448 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cholesterol homeostasis IMP
IMP: Inferred from mutant phenotype
12746448 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17727637 MGI
located in early endosome IDA
IDA: Inferred from direct assay
12746448 MGI
located in neurofilament IDA
IDA: Inferred from direct assay
17727637 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

low density lipoprotein receptor adapter protein 1

  • LDL receptor adaptor protein

  • autosomal recessive hypercholesterolemia protein homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-181997 LDLRAP1-IN-1 Inhibitor / Unkown
HY-RS07580 LDLRAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ldlrap1 NCBI NCBI:26119