2. Gene
  3. Apela - apelin receptor early endogenous ligand Gene

Apela - apelin receptor early endogenous ligand Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ela; Ende; Elabela; Gm10664

Gene ID: 100038489 | Gene type: protein coding

About Apela

Summary

Predicted to enable apelin receptor binding activity and hormone activity. Involved in circulatory system development and positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis. Acts upstream of or within SMAD protein signal transduction. Located in extracellular space. Is expressed in several structures, including embryo ectoderm; embryo endoderm; gut; heart; and metanephros. Used to study pre-eclampsia. Orthologous to human APELA (apelin receptor early endogenous ligand). [provided by Alliance of Genome Resources, Apr 2022]

Apela Products(2)

mRNA Protein Name
NM_001297554.2 NP_001284483.1 apelin receptor early endogenous ligand precursor
NM_001399422.1 NP_001386351.1 apelin receptor early endogenous ligand precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in coronary vasculature development IMP
IMP: Inferred from mutant phenotype
28890073 MGI
involved in embryonic heart tube development IMP
IMP: Inferred from mutant phenotype
28663440 MGI
involved in placenta blood vessel development IMP
IMP: Inferred from mutant phenotype
28663440 MGI
involved in positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis IMP
IMP: Inferred from mutant phenotype
28890073 MGI
acts upstream of or within regulation of blood pressure IMP
IMP: Inferred from mutant phenotype
32829380 MGI
involved in vasculogenesis IMP
IMP: Inferred from mutant phenotype
28663440 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
28663440 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

apelin receptor early endogenous ligand

Protein Elabela

protein Toddler

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00814 APELA Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Apela NCBI NCBI:100506013