2. Gene
  3. Mir107 - microRNA 107 Gene

Mir107 - microRNA 107 Gene

  • Gene
  • Agent
  • Ortholog
Rattus norvegicus

Also known as rno-mir-107

Gene ID: 100314022 | Gene type: ncRNA

About Mir107

Summary

MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]

Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to hypoxia IEP
IEP: Inferred from expression pattern
26294080 RGD
involved in positive regulation of angiogenesis IMP
IMP: Inferred from mutant phenotype
26294080 RGD
involved in positive regulation of endothelial cell migration IMP
IMP: Inferred from mutant phenotype
26294080 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
29262398 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Agents

Pre-clinical Phase
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-R00057 hsa-miR-107 mimic 95.24% Unkown
HY-RI00057 hsa-miR-107 inhibitor 97.55% Unkown
HY-R00057A hsa-miR-107 agomir 96.13% Unkown
HY-RI00057A hsa-miR-107 antagomir 99.60% Unkown
HY-R02570 mmu-miR-107-5p mimic / Unkown
HY-R02570A mmu-miR-107-5p agomir / Unkown
HY-R04210 rno-miR-107-5p mimic / Unkown
HY-R04210A rno-miR-107-5p agomir / Unkown
HY-RI02570 mmu-miR-107-5p inhibitor / Unkown
HY-RI02570A mmu-miR-107-5p antagomir / Unkown
HY-RI04210 rno-miR-107-5p inhibitor / Unkown
HY-RI04210A rno-miR-107-5p antagomir / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mir107 NCBI NCBI:406901