mmu-miR-107-5p antagomir
Based on 1 publication(s) in Google Scholar
mmu-miR-107-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
For research use only. We do not sell to patients.
- Molecular Weight:7803.15
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) mmu-miR-107-5p antagomir
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Biological Activity
Chemical Information
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Molecular Weight 7803.15
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
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miRBase Accession Number
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Mature miRNA Sequence
AGCUUCUUUACAGUGUUGCCUUG
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Stem-loop ID
mmu-mir-107
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Stem-loop Sequence
UUCUCUGUGCUUUCAGCUUCUUUACAGUGUUGCCUUGUGGCAUGGAGUUCAAGCAGCAUUGUACAGGGCUAUCAAAGCACAGAGAGC
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Species
Mouse, Chicken, Columba livia, Dasypus novemcinctus, Guinea pig, Pteropus alecto, Python bivittatus, Rabbit, Rhesus monkey, Salmo salar, Xenopus laevis
Publications (1)
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Journal Impact Factor
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Most Recent
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Biochem Pharmacol
Exosome-derived miR-107 targeting caveolin-1 promotes gallstone progression by regulating the hepatobiliary cholesterol secretion pathway. [Abstract]2025 Feb:232:116735. PMID: 39725331
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)