2. Gene
  3. Mir200a - microRNA 200a Gene

Mir200a - microRNA 200a Gene

  • Gene
  • Agent
  • Ortholog
Rattus norvegicus

Also known as rno-mir-200a

Gene ID: 100314194 | Gene type: ncRNA

About Mir200a

Summary

MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]

Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in response to alkaloid IEP
IEP: Inferred from expression pattern
30240970 RGD
involved in response to hormone IEP
IEP: Inferred from expression pattern
30240970 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Agents

Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-R00405 hsa-miR-200a-3p mimic 96.91% Unkown
HY-R00405A hsa-miR-200a-3p agomir 99.38% Unkown
HY-RI00405 hsa-miR-200a-3p inhibitor 98.85% Unkown
HY-R04282 rno-miR-200a-5p mimic 95.93% Unkown
HY-RI04282 rno-miR-200a-5p inhibitor 98.72% Unkown
HY-RI00405A hsa-miR-200a-3p antagomir 98.85% Unkown
HY-R04282A rno-miR-200a-5p agomir / Unkown
HY-RI04282A rno-miR-200a-5p antagomir / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mir200a NCBI NCBI:406983