2. Gene
  3. Mir212 - microRNA 212 Gene

Mir212 - microRNA 212 Gene

  • Gene
  • Agent
  • Ortholog
Rattus norvegicus

Also known as rno-mir-212

Gene ID: 100314247 | Gene type: ncRNA

About Mir212

Summary

MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]

Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of hydrogen peroxide-mediated programmed cell death IMP
IMP: Inferred from mutant phenotype
23585551 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Agents

Pre-clinical Phase
Bioactive Molecules (16)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RI00443 hsa-miR-212-5p inhibitor 99.47% Unkown
HY-R00442 hsa-miR-212-3p mimic 94.10% Unkown
HY-R00443 hsa-miR-212-5p mimic 92.87% Unkown
HY-RI00442 hsa-miR-212-3p inhibitor 93.58% Unkown
HY-RI00442A hsa-miR-212-3p antagomir 99.80% Unkown
HY-R00442A hsa-miR-212-3p agomir / Unkown
HY-R00443A hsa-miR-212-5p agomir / Unkown
HY-R02825 mmu-miR-212-3p mimic / Unkown
HY-R02825A mmu-miR-212-3p agomir / Unkown
HY-R04302 rno-miR-212-5p mimic / Unkown
HY-R04302A rno-miR-212-5p agomir / Unkown
HY-RI00443A hsa-miR-212-5p antagomir / Unkown
HY-RI02825 mmu-miR-212-3p inhibitor / Unkown
HY-RI02825A mmu-miR-212-3p antagomir / Unkown
HY-RI04302 rno-miR-212-5p inhibitor / Unkown
HY-RI04302A rno-miR-212-5p antagomir / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mir212 NCBI NCBI:406994